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Scientific Presentations

2020(Click on image to enlarge)

AACR (Virtual)
In Vivo Mouse Model Data Demonstrating Reduction in Tumor Cell Proliferation Following Intra-tumoral Administration of TYME-18
Poster 2764
🔊Poster Audio Commentary

AACR (Virtual)
In Vitro and In Vivo Anticancer Effects of D/L-alpha-metyrosine (SM-88), A Novel Metabolism-Based Therapy
Poster 5998
🔊Poster Audio Commentary

ASCO GI (San Francisco, CA)
An Assessment of the Total Cost of Pancreatic Cancer Using Real-World Evidence
Abstract 773

ASCO GI (San Francisco, CA)
TYME-88-Panc Part 2: A Randomized Phase 2/3 of SM-88 with MPS as Third-Line in Metastatic PDAC
Abstract TPS789

2019

ESMO Congress (Barcelona, Spain)
Phase II Trial of SM-88 in Non-Metastatic Biochemical Recurrent Prostate Cancer 
Abstract: 3611

ESMO Congress (Barcelona, Spain)
Phase II Monotherapy Efficacy of Cancer Metabolism Targeting SM-88 in Heavily Pre-Treated PDAC Patients
Abstract: 4283

AACR Special Conference (Boston, MA)
CTC-based Efficacy of SM-88 Correlates with Overall Survival in Advanced Pancreatic Cancer
Abstract: 54116822

AACR Special Conference (Boston, MA)
Therapeutic Potential of Targeting Amino Acid Metabolism in Pancreatic Cancer
Abstract: 78677080

ESMO World GI (Barcelona, Spain)
SM-88 Therapy In High-risk Poor Prognosis Pancreatic Cancer
Abstract: 160

ASCO GU (San Francisco, CA)
Evaluating Non-hormonal Therapy in a Phase II Trial of SM-88 for Rising PSA Prostate Cancer
Abstract: 83

ASCO GU (San Francisco, CA)
Typical Hormone Deprivation Side Effects Compared to SM-88 Therapy for Rising PSA
Abstract: 79

ASCO GI (San Francisco, CA)
Phase II Trial of SM-88 in Patients with Metastatic Pancreatic Cancer: Preliminary Results of the 1st Stage
Abstract: 200 (rev.1/18/19 10:43 AM ET)

ASCO GI (San Francisco, CA)
Phase II Pharmacokinetics of Oral SM-88 in Heavily Pre-Treated Advanced Pancreatic Ductal Adenocarcinoma (PC)
Abstract: 277

ASCO GI (San Francisco, CA)
Feasibility of SM-88 in Pancreatic Cancer After Multiple Prior Lines and ECOG ≤ 2
Abstract: 310

ASCO GI (San Francisco, CA)
Designing Clinical Trials in 3rd Line or Greater Pancreatic Cancer
Abstract: 226

2018

ASCO General Meeting Poster TPS4156 SM-88 in Advanced Cancers of the Pancreas

ASCO General Abstract e13100 SM-88 Efficacy and Safety in Metastatic Breast Cancers

ASCO General Abstract e24072 Prospective Comparison of Invasive Circulating Tumor Cells (iCTCs) vs PSA and mPFS in Prostate Cancer (PC) Treated with SM-88

ASCO General Abstract e14535 SM-88 Efficacy Across Multiple High-Risk Factors

ASCO General Abstract e14528 Comparison of SUV and RECIST Responses in Cancers Treated with SM-88

ASCO GU Poster 2018 Phase II Trial of SM-88 in Non-Metastatic Biochemical Recurrent Prostate Cancer

ASCO GI Poster 2018 SM-88 Therapy in Patients with Advanced or Metastatic Pancreatic Cancer

2017

ASCO 2017

ASCO Poster 2017 – A Phase 1b/2, Open-Label, Dose Escalation Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of TYME-88 (SM-88) in Patients with Prostate Cancer

A phase Ib/II, open-label, dose escalation study to evaluate the safety, pharmacokinetics, and efficacy of SM88 in patients with prostate cancer. Abstract: TPS2615

SMK/SM88 toxicity, efficacy, and patient-reported outcomes in metastatic pancreas cancer. Abstract: e14060

Phase Ib pharmacokinetics of non-hormonal SM88 in patients with non-metastatic recurrent prostate cancer. Abstract: E14061

SM88/SMK non-hormonal therapy in recurrent or untreated prostate cancer. Abstract: E16540

SM88 in non-metastatic rising PSA-recurrent prostate cancer. Abstract: E16567

ESMO 2017

ESMO 2017 SM-88 Poster. September 2017

2016

ESMO 2016 Preclinical Data Poster. October 2016